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I was considering the horns, and there was another horn, a little one, coming up among them, before whom three of the first horns were plucked out by the roots. And there, in this horn, were eyes like the eyes of a man, and a mouth speaking pompous words. Daniel 7:8

And he was given a mouth speaking great things and blasphemies, and he was given authority to continue for forty-two months. Revelation 13:5

666 = Lateinos

From Wikipedia

The term or title antichrist, in Christian theology, refers to a leader who fulfills Biblical prophecies concerning an adversary of Christ, while resembling him in a deceptive manner. The antichrist will seemingly provide for the needs of the people but deny them ultimate salvation.

The term "antichrist" appears five times in 1 John and 2 John of the New Testament — once in plural form and four times in the singular.[1] The Apostle Paul's Second Epistle to the Thessalonians, in particular the 2nd chapter, summarizes the nature, work, coming, and revelation of the "Man of Sin" - a passage often regarded as referring to same person as the antichrist of 1 and 2 John.

Polycarp (ca. 69 – ca. 155) warned the Philippians that everyone that preached false doctrine was an antichrist.[28]

Irenaeus (2nd century AD - c. 202) held that Rome, the fourth prophetic kingdom, would end in a tenfold partition. The ten divisions of the empire are the "ten horns" of Daniel 7 and the "ten horns" in Revelation 17. A "little horn," which is to supplant three of Rome's ten divisions, is also the still future "eighth" in Revelation.[29][30]

Irenaeus identified the Antichrist with Paul's Man of Sin, Daniel's Little Horn, and John's Beast of Revelation 13.[31] He sought to apply other expressions to Antichrist, such as "the abomination of desolation," mentioned by Christ (Matt. 24:15) and the "king of a most fierce countenance," in Gabriel's explanation of the Little Horn of Daniel 8.[32][33]

Under the notion that the Antichrist, as a single individual, might be of Jewish origin, Irenaeus fancies that the mention of "Dan," in Jeremiah 8:16, and the omission of that name from those tribes listed in Revelation 7, might indicate Antichrist's tribe.[34] He also speculated that it was “very probable” the Antichrist might be called Lateinos, which is Greek for “Latin Man”.[35]